A new high-frequency allele of the BM2113 locus in the Yunnan mithun population.

نویسندگان

  • K-X Qu
  • Z-X He
  • R-J Hao
  • J-C Zhang
  • B-Z Huang
  • L-S Zan
  • Y-P Zhang
چکیده

The BM2113 locus was amplified in Yunnan mithun (Bos frontalis) from the southwest mountains of China. It showed a high degree of polymorphism with a total of 12 alleles. The 121-bp polymorphic allele of the BM2113 locus that accounted for 37.1% of homozygotes was the predominant allele with a frequency of 58.57%, identified as mithun-specific for Bos species in Yunnan mithun. The polymorphism information content value was high with a mean of 0.6170, the expected and observed heterozygosity was moderate with values of 0.6427 and 0.6000, respectively, and the BM2113 locus was under Hardy-Weinberg equilibrium (P = 0.2897) in the Yunnan mithun population. This study elucidated the genetic diversity, multi-origin, specific alleles, and characterization of mithun.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Null Allele Frequencies at HLA-G Locus in Iranian Healthy Subjects

Background: HLA-G gene contains 15 alleles including a null allele, HLA-G*0105N. Previous studies have shown that HLA-G*0105N does not encode the complete HLA-G1 or HLA-G5 isoforms but encodes a functional HLA-G protein with the ability to in-hibit NK cell cytolysis. Thus, although the biological functions of HLA-G1 and HLA-G5 proteins are abrogated, other isoforms such as HLA-G2 can replace th...

متن کامل

Investigation of Polymorphism of some Microsatellite Markers in Baluchi Sheep Population

     Due to the importance of conservation and preserving indigenous breeds, Baluchi sheep was selected as the most populous breed of Iranian sheep and reliable pedigree. In this study genetic variation were analyzed with 15 microsatellites markers (BM737, BM1815, BMS332, BMS995, BMS2721, KD101, LSCV36, LSCV38, McM63, McM139, McM214, McMA1, McMA10, OarVH110, TGLA231) in a population of Baluchi ...

متن کامل

Genotype and allele frequency of CYP2C19*17 in a healthy Iranian population

  Background: Cytochrome P450 2C19 (CYP2C19) is important in metabolism of wide range of drugs. CYP2C19*17 is a novel variant allele which increases gene transcription and therefore results in ultra-rapid metabolizer phenotype (URM). Distribution of this variant allele has not been well studied worldwide. The aim of present study was to investigate allele and genotype frequencies of CYP2C19*17 ...

متن کامل

Allelic Variation of VRN-1 Locus in Iranian Wheat Landraces

Wheat is a crop with spring and winter types and wide adaptability to different climate conditions. The wide adaptability of wheat is mainly controlled by three groups of genetic factors and among them vernalization (VRN) genes play pivotal role in determining spring and winter types. In this study, 395 Iranian wheat landraces were characterized with specific primer pairs designed based on VRN-...

متن کامل

Frequencies of HLA-A, B and DRB1 alleles in a large normal population living in the city of Mashhad, Northeastern Iran

Objective(s): The population in Iran is a genetic admixture of the ancestral Aryan and other populations neighboring Iran. Different ethnic groups in Iran show wide regional distributions for many human leukocyte antigen (HLA) alleles. Therefore, it is necessary and sensible to study the differences in HLA allele distribution in different area. We studied the HLA class I and II allele frequenci...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Genetics and molecular research : GMR

دوره 13 1  شماره 

صفحات  -

تاریخ انتشار 2014